In Vitro Proximity and Ubiquitylation Assays for CRBN, VHL and Emerging Ligases of Interest in TPD Introduction Trilogy offers top-quality products and custom services. Our innovative in vitro assays complement cell-based methods, providing valuable insights in TPD workflows. We feature HTS-compatible reagents and assays for screening and mechanistic studies, including highly active enzymes such as […]
Well-characterized and emerging E3 ligase reagents to support ubiquitin biology, targeted protein degradation, mechanistic enzymology, and drug discovery research.
F-box ligase reagents enable precise investigation of substrate recognition, ubiquitin-mediated degradation, and targeted protein degradation pathways.
F-box ligase reagents enable precise investigation of substrate recognition, ubiquitin-mediated degradation, and targeted protein degradation pathways.
Interrogate Ubiquitin Signaling and Protein Dynamics with Defined Polyubiquitin Chains Trilogie Bioscience’s defined polyubiquitin chains enable targeted investigation of ubiquitin signaling, protein degradation, DNA repair, autophagy, immune signaling, and protein trafficking pathways. These research-use-only reagents are enzymatically assembled from wild-type ubiquitin and manufactured with defined linkage specificity, controlled chain length, and high purity to support […]
