Accelerating Discovery in Ubiquitin Proteasome Biology, Targeted Protein Degradation, and Induced Proximity
Functionally validated enzymes, proteins, and in vitro assays enabling mechanistic studies and therapeutic innovation
What We Offer
Explore Trilogie's reagents, custom services, and scientific resources for UPS biology and targeted protein degradation.
Products
UPS Reagent Catalog
Browse Trilogie’s catalog of ubiquitin pathway reagents for targeted protein degradation and UPS biology research.
Services
Custom Services
Work with Trilogie scientists on assay development, protein expression, purification, and mechanism-focused UPS workflows.
Resource
E3 Ligases
Well-characterized and emerging E3 ligase reagents to support ubiquitin biology, targeted protein degradation, mechanistic enzymology, and drug discovery research.
Resource
DCAF Ligases
DCAF ligase reagents enable targeted investigation of CRL4-mediated ubiquitination, substrate recognition, and selective protein degradation pathways.
Resource
F-Box Ligases
F-box ligase reagents enable precise investigation of substrate recognition, ubiquitin-mediated degradation, and targeted protein degradation pathways.
Resource
Defined Polyubiquitin Chains
Defined polyubiquitin chains enable targeted investigation of ubiquitin signaling, protein degradation, DNA repair, autophagy, immune signaling, and protein trafficking pathways.
Design, expression optimization, and production are conducted at our Worcester, MA facility
Meet the Scientific Team
Work directly with scientists experienced in UPS biology, targeted protein degradation, assay development, and protein production.
Rapidly expanding solutions for cutting-edge science
Explore validated reagents, custom assay development, and scientific expertise for targeted protein degradation research.